Endocrine Abstracts

The specialized endocrine cell types of pancreatic islets of Langerhans are essential for maintaining glucose homeostasis. Bulk approaches to characterize islets in normal and diabetic conditions are challenging, as both cell-type specific gene expression changes, changes in the composition of islets, and changes in cell types including de- and trans-differentiation can contribute. Furthermore, technologies to isolate specific cell types from human islets are often lacking, an...